Staff scientist in international research group working on epigenetic / Noncoding RNA mediated control of meetabolism - #335732

Syddansk Universitet


Dato: for 1 uge siden
By: Odense, Region Syddanmark
Kontrakttype: Fuld tid

A position as Staff Scientist (A-TAP salary level) is available at the Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, from the 1st of June 2024.

The employee will be part of Professor Jan-Wilhelm Kornfeld’s DDEA (Danish Diabetes and Endocrine Academy) funded research group (www.kornfeldlab.com), which is interested in understanding the role of Noncoding RNAs such as miRNAs and epigenetic (chromatin) processes that regulate energy metabolism, with a focus on adipose (fat) tissue regulation in obese rodent models and patients. In our work we utilize multimodal -omics methods such as (small) RNA-Seq, computational approaches, and transgenic mice to identify and molecularly characterize disease-associated Noncoding RNAs and chromatin signatures in vivo.

We are seeking an employee (biologist, bioinformatician or related field within biomedicine) who can independently conceptualise and carry out research projects, is actively involved in the groups’ research projects and appreciates being a central part of an ambitious, international team of scientists.

The ideal candidate excels in one or many of the following techniques:

  • Assisting in preparing adipose tissues and cells for omic (transcriptomic, proteomic and metabolomics) analyses.
  • Contributing to research activities in the group by computational support.
  • Analysing NGS datasets from mouse and human tissues.
  • Developing novel methods for genome-wide understanding of Noncoding RNA function in mice (AGO2-CLIP).
  • Aiding in husbandry, handling and phenotyping of transgenic mice.
  • Assisting training of undergraduate students and guest scientists.
  • Contributing to teaching activities in English in the group and for the Department.

Preferred education and background:

  • A PhD degree in life sciences and / or computer sciences.
  • Experience in Noncoding RNA biology and biochemistry.
  • Experience in characterising (transgenic) mouse models of metabolic disease.
  • Ideally one first authorship published in a leading journal in the field (or under submission to a visible journal in the field).
  • Proficiency in R or one other main programming languages (e.g. Python).
  • Willingness to receive additional training in computational analyse and integration of omics data.
  • Good collaborative skills, a positive attitude towards science and its contribution to society.
  • A supportive, pragmatic colleague with contagious optimism to overcome challenges in academic research.
  • High diligence and the intellectual and time flexibility required for an academic position.
  • Overall: An open and positive mind that actively contributes to the infrastructure and the success of the research team and the Department.

Further information can be obtained from Professor Jan-Wilhelm Kornfeld interim email: [email protected] phone +45 9350 7481

Employment shall take place in accordance with the framework agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations).

Application must include cover letter, CV and certificate. All documents in connection with the application should not contain CPR number (civil registration number) – in that case, the CPR number must be crossed out.

All attached files must be in Adobe PDF format. Cover letter and CV can contain max. 5 Mb. Application deadline 26 February 2024.

We recommend that you read how to apply before you apply.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

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